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The N-Terminus of Dictyostelium Scar Interacts with Abi and HSPC300 and Is Essential for Proper Regulation and Function

Scar/WAVE proteins, members of the conserved Wiskott-Aldrich syndrome (WAS) family, promote actin polymerization by activating the Arp2/3 complex. A number of proteins, including a complex containing Nap1, PIR121, Abi1/2, and HSPC300, interact with Scar/WAVE, though the role of this complex in regul...

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Bibliographic Details
Main Authors: Caracino, Diana, Jones, Cheryl, Compton, Mark, Saxe, Charles L.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855017/
https://ncbi.nlm.nih.gov/pubmed/17314411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-06-0518
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