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Conformational Dynamics of the Major Yeast Phosphatidylinositol Transfer Protein Sec14p: Insight into the Mechanisms of Phospholipid Exchange and Diseases of Sec14p-Like Protein Deficiencies

Molecular dynamics simulations coupled with functional analyses of the major yeast phosphatidylinositol/phosphatidylcholine transfer protein Sec14p identify structural elements involved in regulating the ability of Sec14p to execute phospholipid exchange. The molecular dynamics simulations suggest l...

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Detalhes bibliográficos
Main Authors: Ryan, Margaret M., Temple, Brenda R.S., Phillips, Scott E., Bankaitis, Vytas A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855008/
https://ncbi.nlm.nih.gov/pubmed/17344474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-11-1024
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