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Vasodilator actions of HA1077 in vitro and in vivo putatively mediated by the inhibition of protein kinase.

The in vitro and in vivo vasorelaxant effects of HA1077, 1-(5-isoquinolinesulphonyl)-homopiperazine HCl, a novel vasodilator were examined. The inhibitory effects of HA1077 on contractile responses to various agonists were examined on strips of rabbit aorta. The concentration-response curves to 5-hy...

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Detalhes bibliográficos
Main Authors: Asano, T., Suzuki, T., Tsuchiya, M., Satoh, S., Ikegaki, I., Shibuya, M., Suzuki, Y., Hidaka, H.
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854800/
https://ncbi.nlm.nih.gov/pubmed/2611484
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