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[3H]-idazoxan binds with high affinity to two sites on hamster adipocytes: an alpha 2-adrenoceptor and a non-adrenoceptor site.

1. [3H]-idazoxan labels a single population of high affinity sites (Kd 2.26 +/- 0.02 nM; Bmax 372 +/- 25 fmol mg-1 protein) in hamster adipocyte membranes. In the presence of 1 microM yohimbine to preclude binding to alpha 2-adrenoceptors, the density of [3H]-idazoxan binding sites was reduced (287...

詳細記述

保存先:
書誌詳細
主要な著者: MacKinnon, A. C., Brown, C. M., Spedding, M., Kilpatrick, A. T.
フォーマット: Artigo
言語:Inglês
出版事項: 1989
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854795/
https://ncbi.nlm.nih.gov/pubmed/2558757
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