Side chain modifications in lankacidin group antibiotics.

Novel N-acyl analogs of lankacidin may be prepared from 3-isocyanatolankone diformate [7,13-bis(formyloxy)-2-isocyanato-1,4,10,19-tetramethyl-16- oxabicyclo[13.2.2.]nonadeca-3,5,9,11-tetraen-17,18-dione]. Of seven such analogs evaluated in vitro only homolankacidin diformate showed significant activ...

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Bibliografiske detaljer
Main Authors: McFarland, J W, Pirie, D K, Retsema, J A, English, A R
Format: Artigo
Sprog:Inglês
Udgivet: 1984
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC185479/
https://ncbi.nlm.nih.gov/pubmed/6370129
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