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Thapsigargin, a new calcium-dependent epithelial anion secretagogue.

1. Thapsigargin, a sesquiterpene lactone, was shown to cause electrogenic anion secretion in monolayers of human colonic epithelial cells, an effect which was crucially dependent upon calcium and did not involve eicosanoid formation. 2. To measure the secretory effect calcium needed to be present in...

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Detalhes bibliográficos
Main Authors: Brayden, D. J., Hanley, M. R., Thastrup, O., Cuthbert, A. W.
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854789/
https://ncbi.nlm.nih.gov/pubmed/2511993
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