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Lorazepam discontinuation promotes 'inverse agonist' effects of benzodiazepines.

1. The effects of lorazepam discontinuation on responses to benzodiazepine agonists and antagonists were studied in mice. 2. The convulsant dose of pentylenetetrazol was decreased after an acute dose of lorazepam (0.5 mg kg-1) at 4 days after drug discontinuation, compared to 1 or 7 days after disco...

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Bibliografski detalji
Glavni autori: Schatzki, A., Lopez, F., Greenblatt, D. J., Shader, R. I., Miller, L. G.
Format: Artigo
Jezik:Inglês
Izdano: 1989
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854718/
https://ncbi.nlm.nih.gov/pubmed/2573401
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