Selectivity of bradykinin analogues for receptors mediating contraction and relaxation of the rat duodenum.

1. Bradykinin produces a biphasic response in the rat duodenum that consists of a relaxation (pD2 = 8.44) followed by a contraction (pD2 = 6.91). 2. The B1 agonist des-Arg9-bradykinin produced a contraction (pD2 = 7.16) but no relaxation. Des-Arg9-[Leu8]-bradykinin, which is a B1 antagonist in other...

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Autores principales: Paiva, A. C., Paiva, T. B., Pereira, C. C., Shimuta, S. I.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1989
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854693/
https://ncbi.nlm.nih.gov/pubmed/2553188
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