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Effect of hydrogen peroxide on guinea-pig tracheal smooth muscle in vitro: role of cyclo-oxygenase and airway epithelium.

1. Hydrogen peroxide (H2O2) (0.1 microM-3 mM) induced variable contractions of guinea-pig isolated trachea which were attenuated by catalase (100 u ml-1) and mannitol (15 mM) suggesting that contractions were induced by H2O2 and/or the hydroxyl anion. 2. Epithelial removal potentiated contractile re...

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Autors principals: Rhoden, K. J., Barnes, P. J.
Format: Artigo
Idioma:Inglês
Publicat: 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854660/
https://ncbi.nlm.nih.gov/pubmed/2508982
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