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Contraction of the rat isolated aorta caused by Clostridium perfringens alpha toxin (phospholipase C): evidence for the involvement of arachidonic acid metabolism.

1. Alpha toxin produced by Clostridium perfringens contracted the rat isolated aorta and stimulated release of arachidonic acid in the tissue. 2. Quinacrine did not inhibit contraction caused by the toxin. 3. Indomethacin blocked contraction caused by the toxin in a dose-dependent manner and markedl...

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Autors principals: Fujii, Y., Sakurai, J.
Format: Artigo
Idioma:Inglês
Publicat: 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854495/
https://ncbi.nlm.nih.gov/pubmed/2497921
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