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Electrophysiological effects of E-3753, a new antiarrhythmic drug, in guinea-pig ventricular muscle.

1. The electrophysiological effects of E-3753, a new antiarrhythmic drug, were studied in guinea-pig papillary muscles. 2. E-3753 (10(-7) - 10(-4) M) produced a concentration-dependent decrease in the action potential amplitude and Vmax of the upstroke, shortened the action potential duration (APD)...

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Détails bibliographiques
Auteurs principaux: Delpón, E., Valenzuela, C., Tamargo, J.
Format: Artigo
Langue:Inglês
Publié: 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854430/
https://ncbi.nlm.nih.gov/pubmed/2743087
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