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ICI 204448: a kappa-opioid agonist with limited access to the CNS.

1. A number of compounds were evaluated in an attempt to identify a kappa-opioid receptor agonist with limited access to the central nervous system. 2. Quaternary derivatives of the kappa-opioid agonists tifluadom, U-50488H and ethylketocyclazocine were essentially devoid of opioid activity in a ran...

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Detalhes bibliográficos
Main Authors: Shaw, J. S., Carroll, J. A., Alcock, P., Main, B. G.
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854424/
https://ncbi.nlm.nih.gov/pubmed/2568146
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