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Estimation of affinities and efficacies for kappa-receptor agonists in guinea-pig ileum.

1. Ethylketocyclazocine (EKC) and U50,488H have been employed widely as kappa-receptor agonists in the study of opioid receptor systems. However, the quantification of their agonism in terms of affinities and relative efficacies has not been investigated. 2. In this study, operational model-fitting...

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Detalhes bibliográficos
Main Authors: Leff, P., Dougall, I. G.
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854379/
https://ncbi.nlm.nih.gov/pubmed/2541848
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