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Antagonism of PGD2 vasodepressor responses in the rat in vivo by the novel, selective antagonist, BW A868C.
1. Bolus intravenous injection of prostaglandin D2 (PGD2, 1-160 micrograms kg-1), the hydantoin prostanoid BW245C (0.25-160 micrograms kg-1) or prostacyclin (PGI2, 0.05-0.5 microgram kg-1) caused a dose-dependent fall in systemic arterial blood pressure (BP) in the anaesthetized rat, lasting 2-4 min...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1854345/ https://ncbi.nlm.nih.gov/pubmed/2647205 |
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