The selective carotid arterial vasoconstrictor action of GR43175 in anaesthetized dogs.

1. GR43175 is a highly selective agonist at 5-HT1-like receptors in the dog saphenous vein. This study describes the haemodynamic effects of GR43175 in barbitone-anaesthetized dogs. 2. GR43175 (1-1000 micrograms kg-1, i.v.) produced dose-dependent decreases in carotid arterial blood flow with little...

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Bibliographic Details
Main Authors: Feniuk, W., Humphrey, P. P., Perren, M. J.
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854323/
https://ncbi.nlm.nih.gov/pubmed/2538184
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