Local anaesthetic actions of cocaine: effects on excitatory and inhibitory synaptic responses in the hippocampus in vitro.

1. The basis for the proconvulsant action of cocaine was investigated in the CA1 region of the rat hippocampal slice in vitro. 2. Superfusion with 100 microM cocaine depressed inhibitory and excitatory postsynaptic potentials recorded intracellularly from CA1 pyramidal neurones; both types of potent...

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Bibliographic Details
Main Authors: Dunwiddie, T. V., Proctor, W. R., Tyma, J.
Format: Artigo
Language:Inglês
Published: 1988
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854286/
https://ncbi.nlm.nih.gov/pubmed/2851358
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