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Amino acid pharmacology in neocortical slices: evidence for bimolecular actions from an extension of the Hill and Gaddum-Schild equations.

1. The equivalent circuit of the cortical slice preparation has been analysed to show that the measured d.c. voltages can be used to estimate the Hill coefficient for ligands acting on the pyramidal cell bodies. 2. The Gaddum-Schild equation for agonist-antagonist interactions has been modified for...

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Detalhes bibliográficos
Main Authors: Williams, T. L., Smith, D. A., Burton, N. R., Stone, T. W.
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854217/
https://ncbi.nlm.nih.gov/pubmed/2905185
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