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Effects of sulphonylureas and diazoxide on insulin secretion and nucleotide-sensitive channels in an insulin-secreting cell line.

1. The effects of various sulphonylureas and diazoxide on insulin secretion and the activity of various channels have been studied using tissue culture and patch-clamp methods in an insulin-secreting cell line derived from a rat islet cell tumour. 2. Tolbutamide, glibenclamide and HB699 increased th...

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Detalhes bibliográficos
Main Authors: Sturgess, N. C., Kozlowski, R. Z., Carrington, C. A., Hales, C. N., Ashford, M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854127/
https://ncbi.nlm.nih.gov/pubmed/3146398
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