Antinociception and physical dependence produced by [D-Arg2] dermorphin tetrapeptide analogues and morphine in rats.

1. The antinociceptive effects of [D-Arg2] dermorphin tetrapeptide analogues, H-Tyr-D-Arg-Phe-Gly-NH2 and H-Tyr-D-Arg-Phe-beta-Ala-OH when administered subcutaneously (s.c.) in rats were measured by the tail-flick test. In addition, the appearance of typical withdrawal signs upon cessation of admini...

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Hauptverfasser: Chaki, K., Kawamura, S., Kisara, K., Sakurada, S., Sakurada, T., Sasaki, Y., Sato, T., Susuki, K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854126/
https://ncbi.nlm.nih.gov/pubmed/2905901
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