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A possible role for prostaglandins in the expression of morphine dependence in guinea-pig isolated ileum.

1. The effects of the cyclo-oxygenase inhibitors, indomethacin (1.3 microM) and mefenamic acid (10 microM), were investigated on the naloxone-precipitated withdrawal contracture of the morphine-dependent guinea-pig ileum in vitro. 2. Both indomethacin and mefenamic acid prevented expression of the w...

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Detalhes bibliográficos
Main Authors: Johnson, M. A., Hill, R. G., Hughes, J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853880/
https://ncbi.nlm.nih.gov/pubmed/3134073
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