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Spironolactone inhibition of contraction and calcium channels in rat portal vein.

1. The effects of spironolactone have been studied on the mechanical activity of rat portal vein strips and the calcium channel currents of isolated cells using the patch clamp technique (whole-cell configuration). 2. Spironolactone (50 nM to 0.1 mM) depressed both K+-induced and twitch contractions...

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Detalhes bibliográficos
Main Authors: Dacquet, C., Loirand, G., Mironneau, C., Mironneau, J., Pacaud, P.
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853690/
https://ncbi.nlm.nih.gov/pubmed/3427267
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