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Effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine on human cytomegalovirus replication in vitro.

We studied the effect of a novel purine acyclic nucleoside, 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG), on human cytomegalovirus (HCMV) replication. The susceptibility of HCMV to this drug was monitored in cell culture by plaque reduction assay. HCMV replication of various strains was inhibited...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Mar, E C, Cheng, Y C, Huang, E S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185366/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6316844/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.4.518
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