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pH-dependent stimulation by Ca2+ of prostacyclin synthesis in rat aortic rings: effects of drugs and inorganic ions.

Fresh rat aortic rings were incubated in HEPES-buffered salt solutions. Extracellular Ca2+ stimulated the production of prostacyclin (PGI2), as determined by radioimmunoassay of its stable hydrolysis product 6-oxo-prostaglandin F1 alpha. This action of Ca2+ was modified by H+ over the pH range 8.0-6...

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Hlavní autoři: Ritter, J. M., Frazer, C. E., Taylor, G. W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1987
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853509/
https://ncbi.nlm.nih.gov/pubmed/3300833
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