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Studies on the mechanism by which indomethacin increases the anticancer effect of methotrexate.

The effect of indomethacin on the response of the NC carcinoma to methotrexate has been examined in vivo and in vitro. Survival was prolonged in mice treated with indomethacin 1.25 mg kg-1 twice daily plus methotrexate 4 mg kg-1 daily, compared to mice given either drug alone or controls. Indomethac...

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Detalhes bibliográficos
Main Authors: Bennett, A., Gaffen, J. D., Melhuish, P. B., Stamford, I. F.
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853484/
https://ncbi.nlm.nih.gov/pubmed/3594078
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