Detection of Clonal T-Cell Receptor γ Gene Rearrangements in Paraffin-Embedded Tissue by Polymerase Chain Reaction and Nonradioactive Single-Strand Conformational Polymorphism Analysis

The diagnosis of T-cell lymphoproliferative disorders, which frequently involve the skin and other extranodal sites, is often problematic because of the difficulty in establishing clonality in paraffin-embedded tissue. To this end, we developed a simple, nonradioactive method to detect T-cell recept...

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Bibliographic Details
Main Authors: Signoretti, Sabina, Murphy, Michael, Cangi, Maria Giulia, Puddu, Pietro, Kadin, Marshall E., Loda, Massimo
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 1999
Subjects:
Technical Advances
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853445/
https://ncbi.nlm.nih.gov/pubmed/9916920
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