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Adenoviral Gene Transfer of β3 Integrin Subunit Induces Conversion from Radial to Vertical Growth Phase in Primary Human Melanoma

Expression of the β3 subunit of the αvβ3 vitronectin receptor on melanoma cells is associated with tumor thickness and the ability to invade and metastasize. To address the role of αvβ3 in the complex process of progression from the nontumorigenic radial to the tumorigenic vertical growth phase of p...

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Main Authors: Hsu, Mei-Yu, Shih, Daw-Tsun, Meier, Friedegund E., Van Belle, Patricia, Hsu, Ju-Yu, Elder, David E., Buck, Clayton A., Herlyn, Meenhard
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853416/
https://ncbi.nlm.nih.gov/pubmed/9811334
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