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Effect of mannitol infusions into the internal carotid artery on entry of two antibiotics into the cerebrospinal fluid and brains of normal rabbits.

The rapid infusion of hyperosmolar solutions into the internal carotid artery transiently disrupts the integrity of the blood-brain barrier, permitting entry of substances normally excluded from the nervous system. This study examined the effect of such an infusion on the penetration of vancomycin a...

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Библиографические подробности
Главные авторы: Perkins, B A, Strausbaugh, L J
Формат: Artigo
Язык:Inglês
Опубликовано: 1983
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC185322/
https://ncbi.nlm.nih.gov/pubmed/6416160
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