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The Importance of Bottlenecks in Protein Networks: Correlation with Gene Essentiality and Expression Dynamics
It has been a long-standing goal in systems biology to find relations between the topological properties and functional features of protein networks. However, most of the focus in network studies has been on highly connected proteins (“hubs”). As a complementary notion, it is possible to define bott...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1853125/ https://ncbi.nlm.nih.gov/pubmed/17447836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030059 |
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