The ADP ribosylation factor nucleotide exchange factor ARNO promotes β-arrestin release necessary for luteinizing hormone/choriogonadotropin receptor desensitization

Desensitization of guanine nucleotide binding protein-coupled receptors is a ubiquitous phenomenon characterized by declining effector activity upon persistent agonist stimulation. The luteinizing hormone/choriogonadotropin receptor (LH/CGR) in ovarian follicles exhibits desensitization of effector...

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Autori principali: Mukherjee, Sutapa, Gurevich, Vsevolod V., Jones, Jonathan C. R., Casanova, James E., Frank, Scott R., Maizels, Evelyn T., Bader, Marie-France, Kahn, Richard A., Palczewski, Krzysztof, Aktories, Klaus, Hunzicker-Dunn, Mary
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2000
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC18531/
https://ncbi.nlm.nih.gov/pubmed/10811902
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