Two receptor systems are involved in the plasma clearance of tissue-type plasminogen activator (t-PA) in vivo.

Tissue-type plasminogen activator (t-PA) is a serine protease, catalyzing the initial step in the fibrinolytic process. Intravenously administered t-PA is rapidly cleared from the circulation by the liver. Two distinct clearance mechanisms, which are mediated by the low density lipoprotein receptor-...

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Bibliographic Details
Main Authors: Narita, M, Bu, G, Herz, J, Schwartz, A L
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC185308/
https://ncbi.nlm.nih.gov/pubmed/7635954
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