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Accumulated Clonal Genetic Alterations in Familial and Sporadic Colorectal Carcinomas with Widespread Instability in Microsatellite Sequences

A subset of hereditary and sporadic colorectal carcinomas is defined by microsatellite instability (MSI), but the spectra of gene mutations have not been characterized extensively. Thirty-nine hereditary nonpolyposis colorectal cancer syndrome carcinomas (HNPCCa) and 57 sporadic right-sided colonic...

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Autors principals: Fujiwara, Takato, Stolker, Joshua M., Watanabe, Toshiaki, Rashid, Asif, Longo, Patti, Eshleman, James R., Booker, Susan, Lynch, Henry T., Jass, Jeremy R., Green, Jane S., Kim, Hoguen, Jen, Jin, Vogelstein, Bert, Hamilton, Stanley R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853059/
https://ncbi.nlm.nih.gov/pubmed/9777938
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