Multistep Nature of Metastatic Inefficiency : Dormancy of Solitary Cells after Successful Extravasation and Limited Survival of Early Micrometastases

In cancer metastasis, only a small percentage of cells released from a primary tumor successfully form distant lesions, but it is uncertain at which steps in the process cells are lost. Our goal was to determine what proportions of B16F1 melanoma cells injected intraportally to target mouse liver 1)...

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Bibliographic Details
Main Authors: Luzzi, Keith J., MacDonald, Ian C., Schmidt, Eric E., Kerkvliet, Nancy, Morris, Vincent L., Chambers, Ann F., Groom, Alan C.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853000/
https://ncbi.nlm.nih.gov/pubmed/9736035
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