Induction of Nitric Oxide Synthase and Microglial Responses Precede Selective Cell Death Induced by Chronic Impairment of Oxidative Metabolism

Abnormal oxidative processes including a reduction in thiamine-dependent enzymes accompany many neurodegenerative diseases. Thiamine deficiency (TD) models the cellular and molecular mechanisms by which chronic oxidative aberrations associated with thiamine-dependent enzyme deficits cause selective...

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Main Authors: Calingasan, Noel Y., Park, Larry C. H., Calo, Leonard L., Trifiletti, Rosario R., Gandy, Samuel E., Gibson, Gary E.
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852979/
https://ncbi.nlm.nih.gov/pubmed/9708819
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