Functional interactions of DNA topoisomerases with a human replication origin

The human DNA replication origin, located in the lamin B2 gene, interacts with the DNA topoisomerases I and II in a cell cycle-modulated manner. The topoisomerases interact in vivo and in vitro with precise bonds ahead of the start sites of bidirectional replication, within the pre-replicative compl...

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Detalhes bibliográficos
Main Authors: Abdurashidova, Gulnara, Radulescu, Sorina, Sandoval, Oscar, Zahariev, Sotir, Danailov, Miltcho B, Demidovich, Alexander, Santamaria, Laura, Biamonti, Giuseppe, Riva, Silvano, Falaschi, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852844/
https://ncbi.nlm.nih.gov/pubmed/17290216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601578
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