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Rapamycin-induced inhibition of HTLV-I LTR activity is rescued by c-Myb

BACKGROUND: Rapamycin is an immunosuppressive which represses translation of transcripts harbouring a polypyrimidine motif downstream of the mRNA cap site through the mammalian target of rapamycin complex. It inhibits the abnormal autologous proliferation of T-cell clones containing a transcriptiona...

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Bibliografiske detaljer
Main Authors: Rose, Nicola J, Lever, Andrew ML
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852806/
https://ncbi.nlm.nih.gov/pubmed/17407584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-24
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