Načítá se...

Nova2 Interacts with a Cis-Acting Polymorphism to Influence the Proportions of Drug-Responsive Splice Variants of SCN1A

An intronic polymorphism in the SCN1A gene, which encodes a neuronal sodium-channel α subunit, has been previously associated with the dosing of two commonly used antiepileptic drugs that elicit their pharmacologic action primarily at this ion-channel subunit. This study sought to characterize the f...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Heinzen, Erin L., Yoon, Woohyun, Tate, Sarah K., Sen, Arjune, Wood, Nicholas W., Sisodiya, Sanjay M., Goldstein, David B.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Human Genetics 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852745/
https://ncbi.nlm.nih.gov/pubmed/17436242
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!