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Recognition of clonogenic leukemic cells, remission bone marrow and HLA-identical donor bone marrow by CD8+ or CD4+ minor histocompatibility antigen-specific cytotoxic T lymphocytes.

We investigated whether minor histocompatibility (mH) antigen-specific cytotoxic T lymphocytes (CTL) can discriminate between leukemic hematopoietic progenitor cells (leukemic-HPC) from AML or CML patients, the HPC from their remission bone marrow (remission-HPC), and normal HPC from their HLA-ident...

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Publicat a:J Clin Invest
Autors principals: Faber, L M, van der Hoeven, J, Goulmy, E, Hooftman-den Otter, A L, van Luxemburg-Heijs, S A, Willemze, R, Falkenburg, J H
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1995
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185274/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7635982/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118134
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