Cyclooxygenase-2 Induction by Arsenite through the IKKβ/NFκB Pathway Exerts an Antiapoptotic Effect in Mouse Epidermal Cl41 cells

BACKGROUND: Arsenic contamination has become a major public health concern worldwide. Epidemiologic data show that long-term arsenic exposure results in the risk of skin cancer. However, the mechanisms underlying carcinogenic effects of arsenite on skin remain to be studied. OBJECTIVES: In the prese...

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Autori principali: Ouyang, Weiming, Zhang, Dongyun, Ma, Qian, Li, Jingxia, Huang, Chuanshu
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Institute of Environmental Health Sciences 2007
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852668/
https://ncbi.nlm.nih.gov/pubmed/17450217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.9588
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