Parental Smoking Modifies the Relation between Genetic Variation in Tumor Necrosis Factor-α (TNF) and Childhood Asthma

BACKGROUND: Polymorphisms in the proinflammatory cytokine genes tumor necrosis factor-α (TNF) and lymphotoxin-α (LTA, also called TNF-β) have been associated with asthma and atopy in some studies. Parental smoking is a consistent risk factor for childhood asthma. Secondhand smoke and ozone both stim...

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Main Authors: Wu, Hao, Romieu, Isabelle, Sienra-Monge, Juan-Jose, del Rio-Navarro, Blanca Estela, Anderson, Daniel M., Dunn, Erin W., Steiner, Lori L., del Carmen Lara-Sanchez, Irma, London, Stephanie J.
Format: Artigo
Sprog:Inglês
Udgivet: National Institute of Environmental Health Sciences 2007
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852663/
https://ncbi.nlm.nih.gov/pubmed/17450233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.9740
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