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A novel strategy for the solid-phase synthesis of cyclic lipodepsipeptides

A rapid and efficient Fmoc solid-phase synthesis of cyclic lipodepsipeptide analogue 1 to antibiotic fusaricidin A is described. Our synthetic approach includes resin attachment of the first amino acid via side chain, successful use of combination of four quasi-orthogonal removable protecting groups...

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Autors principals: Stawikowski, Maciej, Cudic, Predrag
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852459/
https://ncbi.nlm.nih.gov/pubmed/17440603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2006.09.116
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