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Antibody-based enrichment of peptides on magnetic beads for mass spectrometry-based quantification of serum biomarkers

A major bottleneck for validation of new clinical diagnostics is the development of highly sensitive and specific assays for quantifying proteins. We previously described a method, Stable Isotope Standards with Capture by Anti-Peptide Antibodies, wherein a specific tryptic peptide is selected as a s...

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Detalles Bibliográficos
Main Authors: Whiteaker, Jeffrey R., Zhao, Lei, Zhang, Heidi Y., Feng, Li-Chia, Piening, Brian D., Anderson, Leigh, Paulovich, Amanda
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852426/
https://ncbi.nlm.nih.gov/pubmed/17241609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2006.12.023
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