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Crystal Structure of Human Cyclin K, a Positive Regulator of Cyclin-dependent Kinase 9

Cyclin K and the closely related cyclins T1, T2a, and T2b interact with cyclin-dependent kinase 9 (CDK9) forming multiple nuclear complexes, collectively referred to as positive transcription elongation factor b (P-TEFb). Through phosphorylation of the C-terminal domain of the RNA polymerase II larg...

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Bibliografiske detaljer
Main Authors: Baek, Kyuwon, Brown, Raymond S., Birrane, Gabriel, Ladias, John A.A.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852425/
https://ncbi.nlm.nih.gov/pubmed/17169370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.11.057
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