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An In Vitro Model of Human Dopaminergic Neurons Derived from Embryonic Stem Cells: MPP(+) Toxicity and GDNF Neuroprotection
Human embryonic stem cells (hESCs) can proliferate indefinitely yet also differentiate in vitro, allowing normal human neurons to be generated in unlimited numbers. Here, we describe the development of an in vitro neurotoxicity assay using human dopaminergic neurons derived from hESCs. We showed tha...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852423/ https://ncbi.nlm.nih.gov/pubmed/17109014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1301125 |
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