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Parallel evolution of conserved non-coding elements that target a common set of developmental regulatory genes from worms to humans

BACKGROUND: The human genome contains thousands of non-coding sequences that are often more conserved between vertebrate species than protein-coding exons. These highly conserved non-coding elements (CNEs) are associated with genes that coordinate development, and have been proposed to act as transc...

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Detalhes bibliográficos
Main Authors: Vavouri, Tanya, Walter, Klaudia, Gilks, Walter R, Lehner, Ben, Elgar, Greg
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852409/
https://ncbi.nlm.nih.gov/pubmed/17274809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-2-r15
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