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Inducer-Modulated Cooperative Binding of the Tetrameric CggR Repressor to Operator DNA

The central glycolytic genes repressor (CggR) controls the transcription of the gapA operon encoding five key glycolytic enzymes in Bacillus subtilis. CggR recognizes a unique DNA target sequence comprising two direct repeats and fructose-1,6-bisphosphate (FBP) is the inducer that negatively control...

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Detalhes bibliográficos
Main Authors: Zorrilla, Silvia, Doan, Thierry, Alfonso, Carlos, Margeat, Emmanuel, Ortega, Alvaro, Rivas, Germán, Aymerich, Stéphane, Royer, Catherine A., Declerck, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852337/
https://ncbi.nlm.nih.gov/pubmed/17293407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.095109
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