Ovariectomy enhances and estrogen replacement inhibits the activity of bone marrow factors that stimulate prostaglandin production in cultured mouse calvariae.

To examine PG production in estrogen deficiency, we studied effects on cultured neonatal mouse calvariae of bone marrow supernatants (MSup) from sham-operated (SHAM), ovariectomized (OVX), or 17 beta-estradiol (OVX+E)-treated mice. MSups were obtained 3 wk after OVX when bone density had decreased s...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Kawaguchi, H, Pilbeam, C C, Vargas, S J, Morse, E E, Lorenzo, J A, Raisz, L G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185228/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7615826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118066
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