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Twisted gastrulation (Tsg) is regulated by Tob and enhances TGF-β signaling in activated T lymphocytes

Quiescent T cells express Tob, an APRO gene family member, which functions as a transcriptional regulator. Subtractive hybridization identified Twisted gastrulation (Tsg) as one of the genes suppressed by Tob. Tsg is a secreted protein that interacts with Drosophila decapentaplegic (Dpp) and its ver...

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Detalhes bibliográficos
Main Authors: Tzachanis, Dimitrios, Li, Lequn, Lafuente, Esther M., Berezovskaya, Alla, Freeman, Gordon J., Boussiotis, Vassiliki A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852213/
https://ncbi.nlm.nih.gov/pubmed/17164348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-006510
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