Inhibition of collagenase and stromelysin gene expression by interferon-gamma in human dermal fibroblasts is mediated in part via induction of tryptophan degradation.
The expression of the matrix-degrading enzymes collagenase and stromelysin is modulated by a variety of biologic and pharmacologic agents. IFN-gamma has potent effects on metalloproteinase production and therefore may play an important role in preventing excessive connective tissue degradation durin...
Sparad:
| I publikationen: | J Clin Invest |
|---|---|
| Huvudupphov: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
American Society for Clinical Investigation
1995
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185221/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7615820/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118058 |
| Taggar: |
Inga taggar, Lägg till första taggen!
|