Inhibitors of cyclic nucleotide phosphodiesterase isozymes type-III and type-IV suppress mitogenesis of rat mesangial cells.

We studied interactions between the mitogen-activated protein kinase (MAPK) signalling pathway and cAMP-protein kinase (PKA) signaling pathway in regulation of mitogenesis of mesangial cells (MC) determined by [3H]thymidine incorporation, with or without added EGF. Forskolin or dibutyryl cAMP strong...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Matousovic, K, Grande, J P, Chini, C C, Chini, E N, Dousa, T P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185213/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7615811/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118049
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