Serotonin Transporter Polymorphism Mediates Vulnerability to Loss of Incentive Motivation Following Acute Tryptophan Depletion

The serotonin (5-HT) system is implicated in incentive motivational processes. The present study utilized the acute tryptophan depletion (ATD) procedure to investigate the effect of temporarily lowering 5-HT synthesis on motivation in healthy volunteers, stratifying the results by allelic variation...

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Hlavní autoři: Roiser, Jonathan P, Blackwell, Andrew D, Cools, Roshan, Clark, Luke, Rubinsztein, David C, Robbins, Trevor W, Sahakian, Barbara J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852058/
https://ncbi.nlm.nih.gov/pubmed/16541086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1301055
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